Pascal Lignier, Julien Estager
Carboxylic acids are promising candidates for new sustainable strategies in organic synthesis. In this paper, we ascertain the potential of ultrasound for the hydrolysis of nitriles into carboxylic acids through the study of key parameters of the reaction: pH, hydrolysis medium, reaction time and activation technique. The positive influence of ultrasound under basic conditions is due to more than mechanical effects of cavitation. Indeed, the rate of hydrolysis is dramatically increased under sonication in NaOH solutions. A radical mechanism involving the oxide anion radical O• is proposed.
@article{0c156aeb-7488-4b85-9ec6-383874a13d8e,
title={Swift and efficient sono hydrolysis of n},
author={Pascal Lignier and Julien Estager},
year={2026},
language={en}
}TY - JOUR TI - Swift and efficient sono hydrolysis of n AU - Pascal Lignier AU - Julien Estager PY - 2026 LA - en ER -
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