Myung-Seob Khil, Shanta Raj Bhattarai
Electric field-driven fiber formation (electrospinning) is developing into a practical means for preparing novel porous filament with unusual structures and affordable mechanical properties. In this study, polycaprolactone (PCL) was dissolved in solvent mixtures of methylene chloride/N,N-dimethyl formamide at varying ratios for electrospinning. The filaments formed through coagulation of the spinning solution were based on the principle of phase separation in polymer solutions. The resulting electrospun porous filaments featured diameters ranging from 0.5 to 12 micrometers. To assess the potential of three-dimensional fabric as scaffold matrices, plain weave was prepared using the porous PCL filament. Growth characteristics of MCF-7 mammary carcinoma cells in these woven fabrics demonstrated the significant influence of the matrix microstructure on cell proliferation. The findings indicate that woven fabrics composed of porous filaments created through electrospinning may be promising candidates for tissue engineering scaffolds.
@article{6afddbd7-5a0e-4f93-9d3f-59d1f3382fd6,
title={Novel fabricated matrix via electrospinn},
author={Myung-Seob Khil and Shanta Raj Bhattarai},
year={2026},
language={en}
}TY - JOUR TI - Novel fabricated matrix via electrospinn AU - Myung-Seob Khil AU - Shanta Raj Bhattarai PY - 2026 LA - en ER -
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