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Chemical and morphological analysis of kidney stones. A double-blind comparative study

Silvia Fernandes Ribeiro da Silva, Djamile Cordeiro de Matos

2010pturologykidney stoneschemical analysismorphologyhealth sciences

Abstract

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Purpose: To compare chemical to morphological kidney stone composition analysis based on a sample of 50 stones retrieved from patients at a nephrology service. Methods: The chemical analysis was performed with a Bioclin® kit, while a 10-mm magnifying glass (10x; Prolabo, Paris, France) was employed in the morphological analysis. Findings obtained with the two methods were compared and classified as concordant (100% agreement), partly concordant (concordant for major components, discordant for minor components) or discordant (discordant for major components). Results: In the chemical analysis, the most commonly observed major component was calcium (70%), followed by oxalate (66%), ammonium (56%), urate (28%) and carbonate (24%). In the morphological analysis, the most commonly observed major components were calcium phosphate and magnesium (32% each), followed by calcium oxalate monohydrate (24%), uric acid and urates (20% each), calcium oxalate dihydrate (18%) and cystine (6%). Infectious kidney stones were identified in 34% and 24% of cases by morphological and chemical analysis, respectively. Thirty-eight percent of the samples were classified as concordant, 52% were partly concordant and 10% were discordant. Conclusion: We suggest kidney stones be routinely submitted to both types of analysis for a better understanding of the mechanisms involved in lithogenesis.

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Cite This Work

@article{842b37f6-d3ba-4759-a5ab-b0ba5cc06c8f,
  title={Chemical and morphological analysis of kidney stones. A double-blind comparative study},
  author={Silvia Fernandes Ribeiro da Silva and Djamile Cordeiro de Matos},
  year={2010},
  language={pt}
}
TY  - JOUR
TI  - Chemical and morphological analysis of kidney stones. A double-blind comparative study
AU  - Silvia Fernandes Ribeiro da Silva
AU  - Djamile Cordeiro de Matos
PY  - 2010
LA  - pt
ER  -

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