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Toxicity assessment and selective leaching characteristics of Cu-Al-Ni shape memory alloys in biomaterials applications

Shih-Hang Chang, Bor-Yann Chen

2016enbiomedicaltoxicityshape memory alloysleachingbiocompatibility

Abstract

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Background: Cu-Al-Ni shape memory alloys (SMAs) possess two-way shape memory effects, superelasticity, and damping capacity. Nonetheless, Cu-Al-Ni SMAs remain promising candidates for use in biomedical applications, as they are more economical and machinable than other SMAs. This study investigates the concentrations of metal ions (Cu²⁺, Al³⁺, and Ni²⁺) potentially leaching from these alloys to assess their toxicity and selective leaching characteristics. Methodology: The investigation involved in vitro assessments, focusing on the corrosion behavior and biocompatibility of Cu-Al-Ni SMAs. The research was aimed at establishing the correlation between ion concentration and negative biological responses. Results: The findings indicate that while the rapid solidification process enhances corrosion resistance, the release of metal ions can compromise biocompatibility, presenting a risk in biomedical applications. Therefore, ensuring that Cu-Al-Ni SMAs meet biocompatibility standards is essential for their safe utilization in medical devices and implants.

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Cite This Work

@article{8664b223-7eb7-4445-87eb-533b0b26f0eb,
  title={Toxicity assessment and selective leaching characteristics of Cu-Al-Ni shape memory alloys in biomaterials applications},
  author={Shih-Hang Chang and Bor-Yann Chen},
  year={2016},
  language={en}
}
TY  - JOUR
TI  - Toxicity assessment and selective leaching characteristics of Cu-Al-Ni shape memory alloys in biomaterials applications
AU  - Shih-Hang Chang
AU  - Bor-Yann Chen
PY  - 2016
LA  - en
ER  -

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