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Solid state nitrogen 14 nuclear magnetic

Veronika Vitzthum, Marc A. Caporini

2026ennitrogen-14 NMRdynamic nuclear polarizationsolid-state NMRmagic angle spinninggyrotronproline

Abstract

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By combining indirect detection of 14N with dynamic nuclear polarization (DNP) using a gyrotron, the signal-to-noise ratio can be dramatically improved and the recovery delay between subsequent experiments can be shortened. Spectra of glassy samples of the amino acid proline doped with the stable bi-radical TOTAPOL rotating at 15.625 kHz at 110 K were obtained in a 400 MHz solid-state NMR spectrometer equipped with a gyrotron for microwave irradiation at 263 GHz. DNP enhancement factors on the order of e /C2440 were achieved. The recovery delays can be reduced from 60 s without radicals at 300 K to 6 s with radicals at 110 K. In the absence of radicals at room temperature, the proton relaxation in proline is inefficient due to the absence of rotating methyl groups and other heat sinks, thus making long recovery delays mandatory. DNP allows one to reduce the acquisition times of 13C-detected 14N spectra from several days to a few hours.

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Cite This Work

@article{8e28417d-0ae3-4af2-891d-74e6a68f43b5,
  title={Solid state nitrogen 14 nuclear magnetic},
  author={Veronika Vitzthum and Marc A. Caporini},
  year={2026},
  language={en}
}
TY  - JOUR
TI  - Solid state nitrogen 14 nuclear magnetic
AU  - Veronika Vitzthum
AU  - Marc A. Caporini
PY  - 2026
LA  - en
ER  -

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