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Dynamic nuclear polarization at 9 T usin

V.S. Bajaj, C.T. Farrar

2026endynamic nuclear polarizationsolid state nmrgyrotron microwavehigh magnetic fieldthermal mixingelectron paramagnetic resonance

Abstract

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In this communication, we report enhancements of nuclear spin polarization by dynamic nuclear polarization (DNP) in static and spinning solids at a magnetic field strength of 9T (250 GHz for g = 2 electrons, 380 MHz for 1H). In these experiments, 1H enhancements of up to 170 ± 50 have been observed in 1-13C-glycine dispersed in a 60:40 glycerol/water matrix at temperatures of 20 K; in addition, we have observed significant enhancements in 15N spectra of unoriented pf1-bacteriophage. Finally, enhancements of ~17 have been obtained in two-dimensional 13C– 13C chemical shift correlation spectra of the amino acid U-13C, 15N-proline during magic angle spinning (MAS), demonstrating the stability of the DNP experiment for sustained acquisition and for quantitative experiments incorporating dipolar recoupling. In all cases, we have exploited the thermal mixing DNP mechanism with the nitroxide radical 4-amino-TEMPO as the paramagnetic dopant. These are the highest frequency DNP experiments performed to date and indicate that significant signal enhancements can be realized using the thermal mixing mechanism even at elevated magnetic fields.

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Cite This Work

@article{b7700cb1-0f07-412c-ba8f-2a35816813ea,
  title={Dynamic nuclear polarization at 9 T usin},
  author={V.S. Bajaj and C.T. Farrar},
  year={2026},
  language={en}
}
TY  - JOUR
TI  - Dynamic nuclear polarization at 9 T usin
AU  - V.S. Bajaj
AU  - C.T. Farrar
PY  - 2026
LA  - en
ER  -

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