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Correction factors for the dynamic measu

J. A. Spriet, J. H. Botterman

2026enmass transferoxygenbiochemical engineeringexperimental methodsmathematical modelingparameter estimation

Abstract

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The experimental determination of the volumetric mass-transfer coefficient based on the use of an oxygen electrode necessitates a comprehensive mathematical model of the experimental system and an effective parameter estimation method to calculate the kla value. The study investigates how the choice of model structures impacts the mass-transfer estimate and provides guidelines for selecting efficient parameter estimation schemes. Furthermore, it introduces correction factors illustrating the effects of structural choices on estimates derived from both the moment and least squares parameter estimation techniques. These correction factors are designed to be utilized in the preliminary phase for a general assessment of specific experimental conditions and during estimation to alleviate computational burdens. The insights gained contribute to a deeper understanding of the complex physico-chemical phenomena affecting the overall volumetric mass-transfer coefficient (kla), essential in various chemical and biochemical applications. This work ultimately aims to enhance the accuracy of mass-transfer coefficient measurements, which play a crucial role in optimizing processes requiring oxygen supply to liquid phases. The conclusions drawn from this research will serve as a basis for advancing methodologies in mass-transfer coefficient evaluations.

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Cite This Work

@article{c425d1da-5881-42ec-af23-bc9ef6d55da8,
  title={Correction factors for the dynamic measu},
  author={J. A. Spriet and J. H. Botterman},
  year={2026},
  language={en}
}
TY  - JOUR
TI  - Correction factors for the dynamic measu
AU  - J. A. Spriet
AU  - J. H. Botterman
PY  - 2026
LA  - en
ER  -

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