Silk-Based Hydrogels for Biomedical Applications

This work explores the potential of silk-based hydrogels for various biomedical applications, with a specific focus on their structural and functional properties. The objective is to evaluate the efficacy of silk fibroin in the development of hydrogels that can be utilized for tissue engineering and bone regeneration. A systematic methodology involves the synthesis of silk fibroin hydrogels, combined with biomimetic graphene oxide, and an assessment of their mechanical properties, biocompatibility, and bioactivity through various in vitro experiments. The results indicate that the composite hydrogels exhibit enhanced mechanical strength and favorable biocompatibility when compared to standard materials. Furthermore, the introduction of biomimetic graphene oxide into the silk fibroin matrix significantly improves the biological performance, demonstrating potential applications in regenerative medicine. This study contributes to the growing body of literature on silk-based materials and their role in advancing biomedical technologies, paving the way for innovative solutions in tissue engineering and regenerative medicine.