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C2 Symmetric chiral diamine ligands for

Hayriye ARAL, Tarık ARAL

2026enchiral recognitiondiamine ligandsamino acidsmandelic acidNMR titrationmolecular recognition

Abstract

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Two novel C2-symmetric chiral diamines containing α-phenylethyl and α-(1-naphthyl)ethyl chiral subunits were prepared with quantitative yields. Enantiomeric recognition properties of these simple structured diamine ligands towards D- and L-amino acid esters and D- and L-mandelic acid were examined by the 1H NMR titration method. These ligands exhibited strong complexation (with Kf up to 2481 M−1) and good enantioselectivity (up to KL/KD = 4.08) towards the mandelic acid enantiomers. The results show that simple structured and easily accessible acyclic C2-symmetrical compounds can also be used for enantiomeric recognition of racemic amino acids and mandelic acid in addition to complex molecules such as crown ethers and other cyclic molecules.

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Cite This Work

@article{d5e1bd20-da8b-4d72-aaa1-17dc0660fc53,
  title={C2 Symmetric chiral diamine ligands for},
  author={Hayriye ARAL and Tarık ARAL},
  year={2026},
  language={en}
}
TY  - JOUR
TI  - C2 Symmetric chiral diamine ligands for
AU  - Hayriye ARAL
AU  - Tarık ARAL
PY  - 2026
LA  - en
ER  -

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