Marko Lazi´ c, Minja Miliˇ ci´ c Lazi´ c
Cu-Al-Ni shape memory alloys (SMAs) are widely known for their better properties in comparison to other SMAs (lower production costs, increased ductility, enhanced machinability, reduced liquidus temperature, and decreased hysteresis), but there is still controversy in terms of the biological properties of these materials. The aim of this study was to evaluate biofunctional performances of Cu-Al-Ni alloy produced by continuous casting. The micro-chemical analysis was investigated by SEM/EDX. Immersion tests performed for seven days were used to estimate the quantity of Cu, Al, and Ni ions released in neutral pH and slightly acidic artificial saliva. To assess the biocompatibility of the Cu-Al-Ni alloy samples, MTT assay on fibroblasts and dental pulp cells was performed in indirect and direct contact with samples after 1, 3, and 7 days. The study revealed that continuous casting enables the primary fabrication of Cu-Al-Ni rods with a shape memory effect. Samples immersed in artificial saliva with 6.5 pH value showed no significant amounts of released ions, despite the high concentration of copper.
@article{d9824568-e0a4-4a64-9757-8b06e81c3af4,
title={Biocompatibility Study of a Cu-Al-Ni Rod Obtained by Continuous Casting},
author={Marko Lazi´ c and Minja Miliˇ ci´ c Lazi´ c},
year={2022},
language={en}
}TY - JOUR TI - Biocompatibility Study of a Cu-Al-Ni Rod Obtained by Continuous Casting AU - Marko Lazi´ c AU - Minja Miliˇ ci´ c Lazi´ c PY - 2022 LA - en ER -
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